This is at version 2016.31 .
1. I used the Right click on sequencer-Generate random effects to generate them against a single model group (covering most models) for the whole song. Each time I tried to save ,xLights would crash (disappear) , without a debug report and with the Windows message - trying to find a solution ....
I have attached the Problem files zip file - after opening the sequence and before attempting to save.
So instead , I selected about 20 seconds at a time generated random , saved, repeated for next 20 secs , saved and did the next 20 seconds etc etc , until the group was filled for the whole song.
On the way , I did get two debug reports which I have attached.
2. I also noticed that the render style appeared to be single strand for most of the effects , so I then changed them to default or per preview to get them to work nicely after realising that was the reason most did not "appear to work".
At the end of the process , I did have the whole song working , off the random generated effects on one model group, having discarded just a few along the way ... (was doing this on the plane) . With a few more minor adjustments , I will use it for my display ! I am sure that to the untrained eye of my audience , it will look good

Can try and repeat the save on the latest version (2016.37) if u wish by extracting from the debug files.