For me, I'm still tweaking some things in my LOR sequences. Since I import them as a Data Layer, it is very simple to update.
Edit your LOR file. Save so that the LMS file is up to date.
Open your Nutcracker file. Go to Settings, Sequence Settings, then to the Data Layer tab. Go the LMS data layer (usually the second +) and then Re-Import. Then click Done.
Once you Save, the new updated ISEQ file is merged with the FSEQ file and your changes are there.
This whole process takes just a minute or so.