I'm running version 4.2.16 on Windows 10 and the past few days I have had nothing but crashing, so much to the point I can't get any sequencing done. I was using 4.2.13, having the same problem, and upgraded to 4.2.16 today but nothing has changed. The software crashes about 2 or 3 minutes after I start the app. I'm not doing anything out of the ordinary, just my normal sequencing, I'm not running any other software that could be slowing my computer down or anything that I can think of that could cause this to happen. I'm at a lose here, any ideas whats going on? I've attached a screen shot of the debug report I get each time.